Japanese researchers found that an enzyme in the brain can regulate appetite July 09, 2015 Source: Xinhuanet The Japanese research team recently announced that in animal experiments, they have clarified the mechanism by which an enzyme in the brain is responsible for mediating appetite. This discovery will help develop new ways to control appetite. Previously, researchers have known that the "sodium-potassium transporter" enzyme present on the surface of the arcuate nucleus of the brain is associated with mediating appetite, but the detailed mechanism has not been known. Researchers at the Japan Autonomous Medical University and the International Medical and Welfare University found that rats were not fed to the fasting state for a whole day, and the function of the "sodium-potassium transporter" was found to be reduced. At this time, after the rat nerve cells were collected and observed, it was found that the function of the nerve cells which reacted with the blood sugar level was also lowered. The team injected intracerebral injections of drugs that impeded the action of the "sodium-potassium transporter" and found that the protein that promotes appetite in the arcuate nucleus increased, and the amount of rats fed increased. The research team pointed out that at present, weight-loss drugs have concerns about side effects such as circulatory disorders, and the enzymes discovered this time only play an important role in appetite, so it will help to develop weight-loss drugs with few side effects in the future.
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