Lab Supply Injection Peptide Goserelin Acetate for Cancer Lhrh

Model NO.: API
Appearence: Wnite Powder
Color: White
Grade: Medicine Grade
Type: Vitamins, Amino Acids and Coenzyme
Application: Used
Packaging Details: 2mg/Vial 1mg/Vial
Trademark: Filter
Transport Package: Plastic Vial(Dedicated for Peptide Packing) or Gla
Specification: 2mg/vial
Origin: Shang Hai
HS Code: 2901291000
Model NO.: API
Appearence: Wnite Powder
Color: White
Grade: Medicine Grade
Type: Vitamins, Amino Acids and Coenzyme
Application: Used
Packaging Details: 2mg/Vial 1mg/Vial
Trademark: Filter
Transport Package: Plastic Vial(Dedicated for Peptide Packing) or Gla
Specification: 2mg/vial
Origin: Shang Hai
HS Code: 2901291000

Quick Detail:

1.Quick Details:

Goserelin Acetate 
Sequence: Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Aza-Gly-NH2
Cas No.: 145781-92-6
Molecular Formula: C61H88N18O16
Molecular Weight: 1269.4
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0% 
Water Content(Karl Fischer): ≤8.0%
Acetate Content(HPIC): ≤10.0%
MS (ESI): Consistent
Mass Balance: 95.0~105.0%

2.Product Description:

Goserelin is a synthetic analogue of a naturally occurring luteinizing-hormone releasing hormone (LHRH). Bioavailability is almost complete. Goserelin is poorly protein bound and has a serum elimination half-life of two to four hours in patients with normal renal function. The half-life increases with patients with impaired renal function. There is no significant change in pharmacokinetics in subjects with liver failure. After administration, peak serum concentrations are reached in about two hours. It rapidly binds to the LHRH receptor cells in the pituitary gland thus leading to an initial increase in production of luteinizing hormone and thus leading to an initial increase in the production of corresponding sex hormones. This initial flare may be treated by co-prescribing/co-administering an androgen receptor antagonist  (Casodex). Eventually, after a period of about 14-21 days, production of LH is greatly reduced due to receptor downregulation, and sex hormones are generally reduced to castrate levels

3.Product Application:

Goserelin acetate is used to treat hormone-sensitive cancers of the breast(in pre- and peri-menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. It may also be used in the treatment of male-to-female transgender people and is favoured above other anti-androgens in some countries, such as the UK. It is available as a 1-month depot and a long-acting 3-month depot.

4.Side Effects:

Goserelin acetate may cause a temporary increase in bone pain and symptoms of prostatic cancer during the first few weeks of treatment. This is known as the tumour flare effect, and is the result of an initial increase inluteinizing hormone production, before the receptors are desensitised and hormonal production is inhibited. The symptoms will disappear, with hormonal inhibition. It is therefore advisable to co-treat with anantiandrogen during the first 2-3 weeks of goserelin treatment, particularly in patients with pre-existing bone symptoms.

5.COA:
 
ITEM SPECIFICATION
Identification: Infrared absorption
Appearance: White crystals or crystalline Powder
Chloride(Cl): ≤0.05%
Sulfate(SO4): ≤0.03%
Iron(Fe): ≤0.003%
Heavy Metals: ≤0.0015%
Loss on drying: ≤0.5%
Residue on Ignition: ≤0.3%
Chromatographic purity: Meet the requirements
Organic volatile impurities: Meet the requirements
Assay: 98.50% ~ 101.5%
 
Name Specification
MT-1 10mg/vial,10vial/kit
MT-2 10mg/vial,10vial/kit
MGF 2mg/vial,10vials/kit
DSIP  2mg/vial,10vials/kit
PT-141 10mg/vial,10vial/kit
Selank 5mg/vial,10vials/kit
GHRP-2 5mg/vial,10vials/kit
GHRP-2 10mg/vial,10vial/kit
GHRP-6 5mg/vial,10vials/kit
GHRP-6 10mg/vial,10vial/kit
PEG MGF 2mg/vial,10vials/kit
Ipamorelin 2mg/vial,10vials/kit
Hexarelin 2mg/vial,10vials/kit
Sermorelin 2mg/vial,10vials/kit
Oxytocin 2mg/vial,10vials/kit
TB500             2mg/vial,10vials/kit
Triptorelin 2mg/vial,10vials/kit
Tesamorelin 2mg/vial,10vials/kit
Gonadorelin 2mg/vial,10vials/kit
Gonadorelin 10mg/vial,10vial/kit
CJC-1295 with DAC 2mg/vial,10vials/kit
CJC-1295 without DAC 2mg/vial,10vials/kit
pentadecapeptide BPC 157 2mg/vial,10vials/kit

 
COA and HPLC:
     Why us ?
 

 

We are the direct factory which is located in zhengzhou, Henan province. We also specialize in  the research, development and production of kinds of Amino Acids,Pharmaceutical Polypeptide,Comestic Polypeptide,Vetenary Peptide and Pharmaceutical APIs. We provide good quality and best price with professinal technique.
 
1.COA HPLC MS be sent on request
2.A-Grade 
3.competitive price 
4.Fast delivery
 
 
 1)Delivery: Immediately by DHL/EMS/TNT within 10 days (If you have Forwarder in China,
 
the better.) 
 
 2)  Payment Terms: T/T or western union 
 
 
Please feel free to contact us if you have any other requirement, we accept custom-made.Most competitive price, best quality and best service will be provided.
 
 
  
 
T:008615294859659
Quick Detail:

1.Quick Details:

Goserelin Acetate 
Sequence: Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Aza-Gly-NH2
Cas No.: 145781-92-6
Molecular Formula: C61H88N18O16
Molecular Weight: 1269.4
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0% 
Water Content(Karl Fischer): ≤8.0%
Acetate Content(HPIC): ≤10.0%
MS (ESI): Consistent
Mass Balance: 95.0~105.0%

2.Product Description:

Goserelin is a synthetic analogue of a naturally occurring luteinizing-hormone releasing hormone (LHRH). Bioavailability is almost complete. Goserelin is poorly protein bound and has a serum elimination half-life of two to four hours in patients with normal renal function. The half-life increases with patients with impaired renal function. There is no significant change in pharmacokinetics in subjects with liver failure. After administration, peak serum concentrations are reached in about two hours. It rapidly binds to the LHRH receptor cells in the pituitary gland thus leading to an initial increase in production of luteinizing hormone and thus leading to an initial increase in the production of corresponding sex hormones. This initial flare may be treated by co-prescribing/co-administering an androgen receptor antagonist  (Casodex). Eventually, after a period of about 14-21 days, production of LH is greatly reduced due to receptor downregulation, and sex hormones are generally reduced to castrate levels

3.Product Application:

Goserelin acetate is used to treat hormone-sensitive cancers of the breast(in pre- and peri-menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. It may also be used in the treatment of male-to-female transgender people and is favoured above other anti-androgens in some countries, such as the UK. It is available as a 1-month depot and a long-acting 3-month depot.

4.Side Effects:

Goserelin acetate may cause a temporary increase in bone pain and symptoms of prostatic cancer during the first few weeks of treatment. This is known as the tumour flare effect, and is the result of an initial increase inluteinizing hormone production, before the receptors are desensitised and hormonal production is inhibited. The symptoms will disappear, with hormonal inhibition. It is therefore advisable to co-treat with anantiandrogen during the first 2-3 weeks of goserelin treatment, particularly in patients with pre-existing bone symptoms.

5.COA:
 
ITEM SPECIFICATION
Identification: Infrared absorption
Appearance: White crystals or crystalline Powder
Chloride(Cl): ≤0.05%
Sulfate(SO4): ≤0.03%
Iron(Fe): ≤0.003%
Heavy Metals: ≤0.0015%
Loss on drying: ≤0.5%
Residue on Ignition: ≤0.3%
Chromatographic purity: Meet the requirements
Organic volatile impurities: Meet the requirements
Assay: 98.50% ~ 101.5%
 
Name Specification
MT-1 10mg/vial,10vial/kit
MT-2 10mg/vial,10vial/kit
MGF 2mg/vial,10vials/kit
DSIP  2mg/vial,10vials/kit
PT-141 10mg/vial,10vial/kit
Selank 5mg/vial,10vials/kit
GHRP-2 5mg/vial,10vials/kit
GHRP-2 10mg/vial,10vial/kit
GHRP-6 5mg/vial,10vials/kit
GHRP-6 10mg/vial,10vial/kit
PEG MGF 2mg/vial,10vials/kit
Ipamorelin 2mg/vial,10vials/kit
Hexarelin 2mg/vial,10vials/kit
Sermorelin 2mg/vial,10vials/kit
Oxytocin 2mg/vial,10vials/kit
TB500             2mg/vial,10vials/kit
Triptorelin 2mg/vial,10vials/kit
Tesamorelin 2mg/vial,10vials/kit
Gonadorelin 2mg/vial,10vials/kit
Gonadorelin 10mg/vial,10vial/kit
CJC-1295 with DAC 2mg/vial,10vials/kit
CJC-1295 without DAC 2mg/vial,10vials/kit
pentadecapeptide BPC 157 2mg/vial,10vials/kit

 
COA and HPLC:
     Why us ?
 

 

We are the direct factory which is located in zhengzhou, Henan province. We also specialize in  the research, development and production of kinds of Amino Acids,Pharmaceutical Polypeptide,Comestic Polypeptide,Vetenary Peptide and Pharmaceutical APIs. We provide good quality and best price with professinal technique.
 
1.COA HPLC MS be sent on request
2.A-Grade 
3.competitive price 
4.Fast delivery
 
 
 1)Delivery: Immediately by DHL/EMS/TNT within 10 days (If you have Forwarder in China,
 
the better.) 
 
 2)  Payment Terms: T/T or western union 
 
 
Please feel free to contact us if you have any other requirement, we accept custom-made.Most competitive price, best quality and best service will be provided.
 
 
  
 
T:008615294859659

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