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Scientists discover new protein prevents diabetes
Medical Network February 1st According to the Hong Kong "East Network" reported on January 30, published in the "National Academy of Sciences" online edition of the study pointed out that the Japanese Kobe Pharmaceutical University professor Jiang Benxian Zhao and associate professor Ikeda Hiroshi's research team found The new protein Fam13a, which prevents metabolic syndrome and diabetes, is expected to be applied to the development of new drugs that will not reduce Fam13a in obese conditions.
The new findings in this study are proteins that help insulin function properly, and are thought to be driving the development of new therapeutic drugs to prevent disease.
The research team said that after the body is fat, the fat cells will become hypertrophy, leading to weakening of insulin, and the risk of symptoms such as metabolic syndrome is increased, but there are also people who are healthy even if they are obese. Therefore, the detailed relationship between obesity and related symptoms cannot be Confirmed.
However, during the experiment, the research team noticed the extremely reduced Fam13a in fat cells when the white mice gained weight. It was found that Fam13a can inhibit the breakdown of other proteins required for the normal functioning of insulin.
Through the manipulation of the genetics, the white mice with Fam13a deficiency also showed mild insulin dysfunction in the normal state, and the blood glucose level of the white mice increased significantly after getting fat. On the other hand, white mice that produced a large amount of Fam13a in fat cells did not have an elevated blood glucose level, indicating that it is more difficult to develop diabetes and other diseases.