Potential genetic toxicity of some perfume substances

At the request of the European Commission, the EU Food Safety Authority issued an opinion on the potential genotoxicity of 26 aroma substances on May 7.

In the first round of assessments, the EU expert group excluded the genetic toxicity of 11 fragrance substances, and the remaining 15 species need further evaluation.

According to the latest data, the expert group found that 13 of them can exclude genotoxicity, while maltol and maltol isobutyrate cannot exclude genotoxicity.

Some of the original reports are as follows:

The Panel on Food Contact Materials,Enzymes,Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 26 flavouring substances from subgroup 2.7 of FGE.19 in the Flavouring Group Evaluation 213.In the first version of FGE .213 the Panel has concluded based on available genotoxicity data that a concern regarding genotoxicity could be ruled out for[FL-no:07.047,07.056,07.057,07.075,07.076,07.080,07.117,07.118,07.119,07.120 and 07.168],but for The remaining 15 substances in subgroup 2.7 further genotoxicity data were required.Based on new submitted genotoxicity data,the Panel concluded in FGE.213Rev1 that the concern regarding genotoxicity could be ruled out for 13 substances in subgroup 2.7[FL-no:02.106,07.008 , 07.010, 07.041, 07.083, 07.089, 07.108, 07.109, 07.127, 07.136, 07.200, 07.224 and 09.305] but not for maltol [FL-no: 07.014] and maltyl isobutyrate.

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