Autism, or autism spectrum disorder, is a multi-characteristic disorder that includes social skills, repetitive behaviors, linguistic and nonverbal communication, and distinctive strengths or differences. We now know that autism is divided into many subtypes, most of which are caused by genetic and environmental interactions. It is estimated that one out of every 68 children has autism. Although, there are many intervention methods for autism. But most lack evidence of evidence-based medicine. There is no optimal treatment, and the best treatment should be individualized treatment. There are severe, moderate, and mild autism. Children with moderate and mild autism can improve their situation through proper education and training in hospitals and formal institutions. Healthy growth, independent living and work like ordinary children. If autistic children lack early scientific intervention, even if they receive treatment in the future, they will not be able to live, work, or even become disabled. Therefore, proper early diagnosis and early treatment play an important role in autism. So far, 61 genetic mutations affecting the risk of autism (including the 18 newly identified) have been identified through the MSSNG genomic database, which covers the entire genome of 5205 autistic families. Dr. Mathew Pletcher, co-author of the project, and vice president of the autism program, said that although the search for autism genes has been intensely studied for ten years, it is noteworthy that we can still discover new autism, Not only are these 18 genes, the discovery of each new gene helps us explain more cases of autism, because different cases correspond to different behavioral effects and many related medical problems. We have linked several of these genes to the common autism treatment environment, and our ultimate goal is to advance the personalized treatment of autism by gaining insight into multiple subtypes. Their findings also illustrate how using whole-genome sequencing to guide today's healthcare. For example, the article describes at least two of autism-related gene mutations associated with risk of seizures, another associated with heart defects, and one associated with adult diabetes. Autism whole- genome sequencing will benefit medical guidance in other fields. The researchers also determined that many of the 18 newly discovered autism genes affect the functioning of a small number of cellular pathways in the brain. All of these pathways affect the development and communication of brain cells. Dr. Pletcher said that 80% of the 61 genes that have been discovered by MSSNG have the potential to develop drug targets. By understanding these common brain pathways and how different genetic mutations change them, personalized, more effective treatments are just around the corner. The research director of the MSSNG project, who is also the director of the Canadian Center for Applied Genomics in Toronto Hospital, said that MSSNG data is synthesizing all known autism into an autism spectrum. For example, mutations in genes that occur in close relatives in the study can cause different phenotypes, such as only one member of the family showing severe autism, while others carrying these mutant genes are milder. This shows that the diversity of nerves is involved in these complex adjustments. The MSSNG database allows us to identify individuals who have not developed autism but who have mutations in autism-related genes, which will have important implications for neuronal diversity studies. Traditional gene mutation analysis only looked for mutations from 1% of the coding DNA. The MSSNG database enables researchers to perform mutational analysis from 3 billion DNA base pairs (ie, the entire human genome). Bulk Garlic Powder,Bulk Organic Garlic Powder,Minced Garlic Powder,Ried Garlic shandong changrong international trade co.,ltd. , https://www.cragriculture.com