Recently, the Chinese research team designed a micro-robot that is expected to transport cells in the human body and has broad application prospects in the fields of precision therapy, regenerative medicine and minimally invasive surgery. A study published in the journal Science and Robotics on the 27th showed that the Sun Dong team of the City University of Hong Kong used 3D laser printing technology to prepare a micro-robot with a spherical hole structure, which is equivalent in size to human hair. diameter. Sun Dong, director of the Department of Mechanical and Biomedical Engineering at the City University of Hong Kong, said that the robot with the "SU-8 photoresist" as its raw material has a thorn-like structure that can serve as a cell attachment point and greatly improve cell loading capacity. Sun Dong said that the surface of the robot is sputtered with a layer of metallic nickel and titanium, so the robot can be driven by a magnetic field. The researchers selected zebrafish as the experimental object, and injected the micro-robot loaded with stem cells into the yolk of the zebrafish (500 to 700 microns in diameter), successfully achieving the purpose of controlling the movement of the micro-robot through the magnetic field inside the complex organism. The researchers also designed a microfluidic chip to simulate the vascular endothelial cell layer and validated the cell release capability of the magnetron micro-robot. Sun Dong said that in the future, it is conceivable to inject a micro-robot carrying functional cells into the human body through a blood vessel, send it to a designated position with the help of a magnetic field, and let the released functional cells enter the tissue to function.
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