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A cerebral aneurysm is a weak point in the blood vessel that raises blood pressure, causing the blood vessels to swell and bulge the blood vessel wall. In the UK, approximately 2% of people suffer from the disease each year. If left untreated, vascular aneurysms can rupture, causing severe pain and causing bleeding into the brain causing brain damage or brain death to life-threatening.
James Byrne, a professor of neuroradiology at John Radcliffe Hospital, and Professor Zhong You, a professor at the School of Engineering, observed the limitations of existing treatments and worked together to design the device.
The technology uses a special laser-cut metal alloy with shape memory that can be released into the catheter during surgery and inserted into the brain, which opens into a tiny mesh tube (shunt). The tube cooperates with the natural blood vessels in the brain. The device changes the blood flow to the aneurysm, thereby healing the wound.
Mike Karim, CEO, said: "Brain aneurysms are a very bad disease. About one-third of patients will eventually die. If left untreated, it will make one-third of survivors permanent. Nerve damage."
Brian Howlett, chairman of Endovascular at Oxford University, said: "We believe that the device will greatly improve the health of patients and is better than existing treatments. Surgeons can use the device accurately and can be used extensively. The patient is to ensure its safety and effectiveness. Our goal is to use this device to treat deeper cerebrovascular diseases, even those that no other device can achieve."
Isis Innovation, a technology commercialization company at Oxford University, supports the research team's patenting of technology, establishing business plans and capturing opportunities in the market.
Dr. Adam Stoten, leader of technology transformation at Isis Innovation, said: "With the emergence of many risk factors, such as cardiovascular and cerebrovascular diseases, hypertension and diabetes, the incidence of diseases is gradually increasing, it is necessary to develop new methods to treat Cerebral artery disease. Endovascular, a good example of collaboration between surgeons and engineers, can effectively improve patient care."
The development of the device was supported by the Wellcome Trust, Technikos and the University. Oxford Endovascular's goal is to continue the study and begin manufacturing equipment into clinical trials while applying for approval from market regulators.
Http://medicalxpress.com/news/2016-01-tiny-mesh-tube-devices-brain.html
New equipment for the treatment of cerebral aneurysms
Recently, clinicians and scientists at Oxford University have developed an advanced miniature metal wire mesh tube device for the treatment of cerebral aneurysms. Oxford University has participated in research and has developed 2m long equipment, and has carried out clinical trials with Oxford Scientific Innovation PLC Investment Company, Parkwalk consultants and other private investors, and ultimately aims to treat thousands of brains worldwide. Aneurysm patients.